WebBeing bacteriostatic, chloramphenicol can antagonize the cidal action of βlactams/ aminoglycosides on certain bacteria. Uses Because of serious (though rare) bone … WebChloramphenicol interferes with the anamnestic immune response; therefore vaccines should never be administered to people or animals while chloramphenicol is being administered. Chloramphenicol may prolong the duration of action of several drugs, including pentobarbital, codeine, phenobarbital, phenytoin, NSAIDs and coumarins.

14.3 Mechanisms of Antibacterial Drugs - OpenStax

WebChloramphenicol and Tiamphenicol inhibit bacterial protein synthesis and have bacteriostatic activity. Chloramphenicol is relatively toxic, and can cause severe agranulocytosis. ... Florfenicol is a thiamphenicol derivative with the same mechanism of action as chloramphenicol (inhibition of protein synthesis). However, it is more active … WebChloramphenicol is a broad-spectrum antimicrobial agent. It acts by inhibiting protein synthesis. Its high lipid solubility results in rapid absorption, a large volume of … story bots coloring sheets

Chloramphenicol - Mechanism of Action, Indications, and Side …

WebChloramphenicol also causes anemia in two different ways. One mechanism involves the targeting of mitochondrial ribosomes within hematopoietic stem cells, causing a … WebAbstract. Macrolides, lincosamides, tetracyclines and chloramphenicol are structurally unrelated antibiotics which share protein synthesis inhibition as their common mechanism of action. Despite their individual differences, they can all be considered broad spectrum antibiotics with practical use for a wide variety of infections. ross macdonald black money