Witrynaβ-Naphthoflavone has been used: as aryl hydrocarbon receptor agonist to elucidate its effect on Cyp1A1 expression in embryos of transgenic cytochrome P450 1A1 (cyp1a) reporter zebrafish; as AhR agonists, to treat primary normal human epidermal keratinocytes (NHEKs) to study about aryl hydrocarbon receptor (AhR) activation by … Witryna18 sie 2010 · Identification Generic Name beta-Naphthoflavone DrugBank Accession Number DB06732 Background. β-Naphthoflavone, also known as 5,6-benzoflavone, …
Alpha Naphthoflavone - an overview ScienceDirect Topics
WitrynaThe structures of CYP1A2 and CYP1B1 could be constructed using the crystallographic data of the complex between α-naphthoflavone and CYP1 enzymes (Sansen et al., … Witryna15 cze 2005 · Adult male Sprague-Dawley rats were pretreated with the CYP1A inducer beta-naphthoflavone (β-NF) (80 mg/kg/day), once daily for 4 days, followed by exposure to hyperoxic environment (O 2 > 95%) or room air (normoxia) for 60 h. Pleural effusions were measured as estimates of lung injury. Activities of hepatic and pulmonary … gears tactics update
RCSB PDB - 4I8V: Human Cytochrome P450 1A1 in complex with …
WitrynaNOVOPHANE Lotion zapobiegający wypadaniu włosów to produkt odpowiadający za intensywne odżywienie i wzmocnienie włosów. Pobudza ich wzrost i zdecydowanie … Witryna20 lip 2015 · Exposure to aristolochic acid I (AAI) can lead to aristolochic acid nephropathy (AAN), Balkan endemic nephropathy (BEN) and urothelial cancer. The induction of hepatic CYP1A, especially CYP1A2, was considered to detoxify AAI so as to reduce its nephrotoxicity. We previously found that baicalin had the strong ability to … WitrynaA progressive decline in T(4)-UGT activity occurred over time in both rat and mouse hepatocyte cultures. Treatment of cultures with various model inducers such as phenobarbital (PB), beta-naphthoflavone (NF) and clofibric acid (CLO) induced a strong increase in T(4)-UGT activity in rat hepatocyte monolayers. d battery contact plate springs