WebSome secondary metabolites identified in various sponge species have antitumor activity. Sea sponges are leaders in their content of biologically active substances in comparison with other marine invertebrates. Some compounds isolated from sponges have complex structures and exhibit biological activity at very low doses [ 4, 5 ]. WebMarine spongean polybrominated diphenyl ethers, selective growth inhibitors against the cancer cells adapted to glucose starvation, inhibits mitochondrial complex II J Nat Med. …
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Web15 Jan 2016 · The inside cover picture shows the mode of action of marine spongean furanosesterterpene, furospinosulin-1, as an inhibitor for hypoxia-adapted cancer cells … WebTwo analogues possessing steric hindered substituents on C-15 of arenastatin A (1), a potent cytotoxic spongean depsipeptide, were synthesized and shown to enhance … Web2 Nov 2009 · The sponge was extracted with acetone. Its lipophilic extract was separated on a silica gel column, followed by reverse-phase HPLC to yield compound 1 as an oil, which … middle names for the name piper